The details of FoldDB ID: fd0350 |
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| Identification | |
|---|---|
| FoldDB ID | fd0350 |
| Three Letter code
Since there is no uniform representation for the non-natural peptides. The three letter code reported here is as it is mentioned in the original article and/or the external database. | H-[L-Val-D-Oxd-L-Lys-D-Oxd]3-L-Ala-P-RB hydrochloride |
| Smiles | |
| Inchi Key | FYMIJKCFZVHBEK-LSYKRPHFSA-N |
| Molecular weight | 2099.2 |
| Molecular formula | C98H137N20O27*ClH*Cl |
| Source | synthetic construct |
| External ID | |
|---|---|
| Reaxys ID | 30798804 |
| Other information | |
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| Application | Bio-comaptible material |
| Foldamer type | α Peptide |
| Activity |
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| Activity ID | Assay name | Cell line | Target Protein | Organism | Assay Category | Value | Unit | Type | Measurement object |
|---|---|---|---|---|---|---|---|---|---|
| fdact0512 | lymphocyte | human | Metabolism/Transport | Low | % uptake | ||||
| fdact0513 | granulocyte | human | Metabolism/Transport | Active | % uptake | ||||
| fdact0514 | granulocyte | human | Metabolism/Transport | Active | % uptake | ||||
| fdact0515 | monocyte | human | Metabolism/Transport | Active | % uptake | ||||
| fdact0516 | HeLa cell line | Metabolism/Transport | Low | % uptake | |||||
| fdact0517 | lymphocyte | human | Metabolism/Transport | Low | % uptake | ||||
| fdact0518 | monocyte | human | Metabolism/Transport | Active | % uptake | ||||
| fdact0519 | HeLa cell line | Metabolism/Transport | Low | % uptake | |||||
| fdact0520 | monocyte | human | In Vitro (Efficacy) | Active | qualitative | cytosolic distribution |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Form Matters: Stable Helical Foldamers Preferentially Target Human Monocytes and Granulocytes | 2017 | Del Secco B., Malachin G., Milli L., Zanna N., Papini E., Cornia A., Tavano R., Tomasini C. | ChemMedChem | ||
