The details of FoldDB ID: fd1058 |
|---|
Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only. To access the experimental 3D structure kindly go to the browse structure tab and look for PDB or CCDC id.
.
.
| Identification | |
|---|---|
| FoldDB ID | fd1058 |
| Smiles | |
| Inchi Key | VEWNGESMCRPKOR-TWMRQAMASA-N |
| Molecular weight | 1459.8 |
| Molecular formula | C73H117F3N12O15 |
| Source | synthetic construct |
| External ID | |
|---|---|
| Reaxys ID | 20227138 |
| Other information | |
|---|---|
| Application | Inhibitors of p53-hDM2, cellular uptake |
| Foldamer type | β Peptide |
| Other type | Bridged β3-Peptide |
| Structure Type | helical |
| Calculated properties | |
|---|---|
| LogP | 4.45000 |
| H Bond Donor | 15 |
| H Bond Acceptor | 27 |
| Polar Surface Area (PSA) | 451.86000 |
| Activity |
|---|
| Activity not reported |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Bridged β3-Peptide Inhibitors of p53-hDM2 complexation: Correlation between affinity and cell permeability | 2010 | Bautista, Arjel D., Appelbaum, Jacob S., Craig, Cody J., Michel, Julien., Schepartz, Alanna | Journal of the American Chemical Society | ||
