The details of FoldDB ID: fd1155 |
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| Identification | |
|---|---|
| FoldDB ID | fd1155 |
| Smiles | |
| Inchi Key | ABYGSLJZNLXKIK-SFURGTFPSA-N |
| Molecular weight | 1005.35 |
| Molecular formula | C55H88N8O9 |
| Other Name
Since there is no uniform representation for the non-natural peptides. This is the name as it is mentioned in the original article and/or the external database. | Fmoc-(beta3-HVal-beta3-HLys-beta3-HLeu)2-OH |
| Source | synthetic construct |
| External ID | |
|---|---|
| Reaxys ID | 8535664 |
| Other information | |
|---|---|
| Application | Antibacterial |
| Foldamer type | β Peptide |
| Other type | β3 peptide |
| Calculated properties | |
|---|---|
| LogP | 6.03700 |
| H Bond Donor | 9 |
| H Bond Acceptor | 17 |
| Polar Surface Area (PSA) | 273.17000 |
| Activity |
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| Activity ID | Assay name | Cell line | Target Protein | Organism | Assay Category | Value | Unit | Type | Measurement object |
|---|---|---|---|---|---|---|---|---|---|
| fdact0811 | Culture Bioassay | In Vitro (Efficacy) | > 100 | µM | IC50 | ||||
| fdact0812 | erythrocyte | human | In Vitro (Efficacy) | hemolytic dose req. to 50 percent > 100 µmol/l | qualitative |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
De Novo Design of Antibacterial β-Peptides | 1999 | Hamuro, Yoshi., Schneider, Joel P., DeGrado, William F. | Journal of the American Chemical Society | ||
