The details of FoldDB ID: fd1152 |
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| Identification | |
|---|---|
| FoldDB ID | fd1152 |
| Other Name
Since there is no uniform representation for the non-natural peptides. This is the name as it is mentioned in the original article and/or the external database. | H-(beta3-HAla-beta3-HLys-beta3-HVal)5-NH2 |
| Source | synthetic construct |
| External ID | |
|---|---|
| Reaxys ID | 9041302 |
| Other information | |
|---|---|
| Application | Antimicrobial |
| Foldamer type | β Peptide |
| Other type | β3peptide |
| Activity |
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| Activity ID | Assay name | Cell line | Target Protein | Organism | Assay Category | Value | Unit | Type | Measurement object |
|---|---|---|---|---|---|---|---|---|---|
| fdact0802 | In Vitro (Efficacy) | 3 | mM | IC50 | |||||
| fdact0803 | In Vitro (Efficacy) | 20 | mg/L | MIC | |||||
| fdact0804 | erythrocyte | human | In Vitro (Efficacy) | 320 | µM | EC50 | HC50 | ||
| fdact0806 | Binding activity | 0.3 | µM | Kd (dissociation constant) |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
De Novo Design, Synthesis, and Characterization of Antimicrobial β-Peptides | 2001 | Liu, Dahui., DeGrado, William F., | Journal of the American Chemical Society | ||
